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AMPK can exert its action both via phosphorylation of PGC1 or in a direct manner. It s referred to as many different names ketogenic diet, low carb diet, low carb high fat , etc. In fact I had a resident come in to our re hab facility in pretty bad shape. Because there is no consensus on exactly what the diet includes, this leaves the door open to thinking it s safe to live on saturated fats and processed foods, says Dr Tang. The keto diet is a popular weight loss strategy, but the benefits extend far beyond this.